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FDA APPROVES NEW ONCE-A-MONTH DOSE OF ACTONEL FOR POSTMENOPAUSAL OSTEOPOROSIS
CINCINNATI, Bridgewater, NJ, April 24, 2008 — The U.S. Food and Drug Administration (FDA) approved a new once-a-month dose (150 mg) of ActonelŽ (risedronate sodium) tablets for the treatment and prevention of postmenopausal osteoporosis. Actonel is approved to reduce the risk of fractures in postmenopausal women with osteoporosis.
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U.S. products

ACTONEL® (risedronate sodium tablets)

Actonel and Actonel with Calcium are prescription medications to treat and prevent postmenopausal osteoporosis. Actonel 5 mg daily is also indicated for the prevention and treatment of glucocorticoid-induced osteoporosis (GIO) in men and women who are either initiating or continuing systemic glucocorticoid treatment (daily dosage equivalent to 7.5 mg or greater of prednisone) for chronic diseases.




Actonel and Your Active Life
You have an active life and you want it to stay that way. But the fact is, your bones may not be as strong as they once were. And even if you feel strong on the outside, your bones can still be vulnerable on the inside. If you are over 50 and postmenopausal, taking care of your bones should be a priority. ACTONEL helps make your bones stronger and less likely to fracture.

Get more information about osteoporosis and Actonel

You should not take ACTONEL if you are allergic to any of the ingredients, if you have low blood calcium (hypocalcemia), have kidneys that work poorly, or cannot stand or sit upright for 30 minutes. Stop taking ACTONEL and tell your doctor if you experience difficult or painful swallowing, chest pain, or severe or continuing heartburn, as these may be signs of serious upper digestive problems. Follow dosing instructions carefully to lower the chance of these events occurring. Side effects are generally mild or moderate and may include back, muscle, bone or joint pain, stomach pain or upset, or constipation. Contact your doctor if symptoms are severe. Tell all of your healthcare providers about all the medicines that you take. See Product Information (PDF). If you have questions, please talk to your doctor.

Actonel is marketed by the Alliance for Better Bone Health, an alliance between P&G Pharmaceuticals and sanofi-aventis U.S. LLC

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